NSF-supported research yields promising experimental vaccine
Updated: May 10, 2020
Team's effort to engineer a universal flu vaccine that can be administered in a single shot is featured in a new NSF story on flu vaccine innovation
The DeLisa and Putnam labs have teamed up for nearly a decade to develop novel vaccines based on bacterial outer membrane vesicles (OMVs), which are a membrane-based nanostructure, in this case engineered from nonpathogenic E. coli, whose outer surface mimics the cell from which it originated. Recently, the Putnam-DeLisa team, along with collaborator Gary Whittaker from the Department of Microbiology and Immunology at Cornell, leveraged the versatility of OMVs, which have shown promise against other deadly pathogens, to create a single-shot vaccine. A new NSF story on flu vaccine innovation featuring this work was published recently.
The work has also been featured in the Cornell Chronicle on September 21, 2017. Links to the original research article and the Chronicle article, entitled "A new kind of influenza vaccine: One shot might do the trick" can be found below.